Rudi Weikard // Wikimedia Commons

Counties with highest COVID-19 infection rates in Alabama

The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.

Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely.

The United States as of Sep. 13 reached over 1 million COVID-19-related deaths and 95.3 million COVID-19 cases, according to Johns Hopkins University. Currently, 67.6% of the population is fully vaccinated, and 48.6% of vaccinated people have received booster doses.

Stacker compiled a list of the counties with highest COVID-19 infection rates in Alabama using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to Sep. 12, 2022. Cumulative cases per 100,000 served as a tiebreaker.

Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.

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#50. Fayette County, AL

– New cases per 100k in the past week: 221 (36 new cases, -12% change from previous week)
– Cumulative cases per 100k: 33,247 (5,420 total cases)
— 8.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 595 (97 total deaths)
— 44.4% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 35.8% (5,829 fully vaccinated)

Prestinian // Wikimedia Commons

#49. Etowah County, AL

– New cases per 100k in the past week: 222 (227 new cases, 0% change from previous week)
– Cumulative cases per 100k: 30,707 (31,403 total cases)
— 0.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 647 (662 total deaths)
— 57.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 41.9% (42,804 fully vaccinated)

Chris Pruitt // wikicommons

#48. Montgomery County, AL

– New cases per 100k in the past week: 227 (514 new cases, -13% change from previous week)
– Cumulative cases per 100k: 28,953 (65,574 total cases)
— 5.4% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 435 (985 total deaths)
— 5.6% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 53.7% (121,542 fully vaccinated)

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#47. Greene County, AL

– New cases per 100k in the past week: 234 (19 new cases, +73% change from previous week)
– Cumulative cases per 100k: 26,002 (2,109 total cases)
— 15.0% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 629 (51 total deaths)
— 52.7% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 52.0% (4,218 fully vaccinated)

Calvin Beale // Wikimedia Commons

#46. Coffee County, AL

– New cases per 100k in the past week: 235 (123 new cases, -20% change from previous week)
– Cumulative cases per 100k: 30,083 (15,746 total cases)
— 1.7% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 459 (240 total deaths)
— 11.4% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.9% (25,093 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#45. Autauga County, AL

– New cases per 100k in the past week: 240 (134 new cases, +6% change from previous week)
– Cumulative cases per 100k: 32,442 (18,125 total cases)
— 6.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 399 (223 total deaths)
— 3.2% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.0% (25,165 fully vaccinated)

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#44. Madison County, AL

– New cases per 100k in the past week: 241 (898 new cases, -24% change from previous week)
– Cumulative cases per 100k: 28,215 (105,215 total cases)
— 7.8% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 267 (997 total deaths)
— 35.2% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 63.7% (237,716 fully vaccinated)

JNix // Shutterstock

#43. Clay County, AL

– New cases per 100k in the past week: 242 (32 new cases, -67% change from previous week)
– Cumulative cases per 100k: 35,323 (4,675 total cases)
— 15.4% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 642 (85 total deaths)
— 55.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 43.0% (5,686 fully vaccinated)

Library of Congress

#42. Lee County, AL

– New cases per 100k in the past week: 244 (401 new cases, -8% change from previous week)
– Cumulative cases per 100k: 26,447 (43,516 total cases)
— 13.6% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 212 (349 total deaths)
— 48.5% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 41.3% (67,882 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#41. Monroe County, AL

– New cases per 100k in the past week: 251 (52 new cases, -13% change from previous week)
– Cumulative cases per 100k: 29,417 (6,099 total cases)
— 3.9% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 391 (81 total deaths)
— 5.1% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.3% (9,192 fully vaccinated)

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#40. Pickens County, AL

– New cases per 100k in the past week: 256 (51 new cases, -38% change from previous week)
– Cumulative cases per 100k: 29,383 (5,856 total cases)
— 4.0% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 542 (108 total deaths)
— 31.6% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 51.0% (10,160 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#39. Henry County, AL

– New cases per 100k in the past week: 256 (44 new cases, -29% change from previous week)
– Cumulative cases per 100k: 30,904 (5,317 total cases)
— 1.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 453 (78 total deaths)
— 10.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 46.1% (7,939 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#38. Conecuh County, AL

– New cases per 100k in the past week: 257 (31 new cases, +29% change from previous week)
– Cumulative cases per 100k: 27,389 (3,305 total cases)
— 10.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 597 (72 total deaths)
— 44.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.7% (5,392 fully vaccinated)

Jodybwiki // Wikimedia Commons

#37. Baldwin County, AL

– New cases per 100k in the past week: 258 (577 new cases, -1% change from previous week)
– Cumulative cases per 100k: 28,970 (64,672 total cases)
— 5.3% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 313 (699 total deaths)
— 24.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 52.2% (116,432 fully vaccinated)

Michael Rivera // Wikimedia Commons

#36. Dale County, AL

– New cases per 100k in the past week: 258 (127 new cases, -27% change from previous week)
– Cumulative cases per 100k: 30,763 (15,127 total cases)
— 0.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 490 (241 total deaths)
— 18.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.6% (23,883 fully vaccinated)

Altairisfar // Wikimedia Commons

#35. Clarke County, AL

– New cases per 100k in the past week: 258 (61 new cases, +69% change from previous week)
– Cumulative cases per 100k: 33,672 (7,954 total cases)
— 10.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 440 (104 total deaths)
— 6.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 51.8% (12,241 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#34. Randolph County, AL

– New cases per 100k in the past week: 264 (60 new cases, -57% change from previous week)
– Cumulative cases per 100k: 25,359 (5,762 total cases)
— 17.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 330 (75 total deaths)
— 19.9% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 33.7% (7,649 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#33. Elmore County, AL

– New cases per 100k in the past week: 273 (222 new cases, -16% change from previous week)
– Cumulative cases per 100k: 33,484 (27,192 total cases)
— 9.4% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 440 (357 total deaths)
— 6.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.5% (38,540 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#32. Crenshaw County, AL

– New cases per 100k in the past week: 305 (42 new cases, +17% change from previous week)
– Cumulative cases per 100k: 31,361 (4,319 total cases)
— 2.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 741 (102 total deaths)
— 79.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 35.2% (4,843 fully vaccinated)

Springfieldohio // Wikimedia Commons

#31. Jackson County, AL

– New cases per 100k in the past week: 308 (159 new cases, -18% change from previous week)
– Cumulative cases per 100k: 32,398 (16,726 total cases)
— 5.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 480 (248 total deaths)
— 16.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 50.4% (26,018 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#30. Cherokee County, AL

– New cases per 100k in the past week: 317 (83 new cases, +22% change from previous week)
– Cumulative cases per 100k: 22,477 (5,888 total cases)
— 26.6% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 332 (87 total deaths)
— 19.4% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 31.6% (8,265 fully vaccinated)

Carol M. Highsmith/Library of Congress // Wikimedia Commons

#29. Houston County, AL

– New cases per 100k in the past week: 317 (336 new cases, +4% change from previous week)
– Cumulative cases per 100k: 28,117 (29,771 total cases)
— 8.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 492 (521 total deaths)
— 19.4% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.1% (46,709 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#28. Marion County, AL

– New cases per 100k in the past week: 320 (95 new cases, +8% change from previous week)
– Cumulative cases per 100k: 31,024 (9,217 total cases)
— 1.4% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 518 (154 total deaths)
— 25.7% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 37.0% (11,000 fully vaccinated)

M Floyd // Flickr

#27. Jefferson County, AL

– New cases per 100k in the past week: 326 (2,147 new cases, +7% change from previous week)
– Cumulative cases per 100k: 32,727 (215,530 total cases)
— 6.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 367 (2,418 total deaths)
— 10.9% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 59.8% (394,120 fully vaccinated)

Wayne James // Shutterstock

#26. Lauderdale County, AL

– New cases per 100k in the past week: 327 (303 new cases, -28% change from previous week)
– Cumulative cases per 100k: 29,944 (27,767 total cases)
— 2.2% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 437 (405 total deaths)
— 6.1% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.6% (44,171 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#25. Calhoun County, AL

– New cases per 100k in the past week: 331 (376 new cases, +21% change from previous week)
– Cumulative cases per 100k: 31,788 (36,113 total cases)
— 3.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 567 (644 total deaths)
— 37.6% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.1% (54,603 fully vaccinated)

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#24. Lawrence County, AL

– New cases per 100k in the past week: 334 (110 new cases, -23% change from previous week)
– Cumulative cases per 100k: 26,424 (8,700 total cases)
— 13.7% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 510 (168 total deaths)
— 23.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.8% (15,732 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#23. Shelby County, AL

– New cases per 100k in the past week: 346 (753 new cases, +17% change from previous week)
– Cumulative cases per 100k: 31,966 (69,590 total cases)
— 4.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 215 (468 total deaths)
— 47.8% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 37.1% (80,706 fully vaccinated)

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#22. Bullock County, AL

– New cases per 100k in the past week: 347 (35 new cases, 0% change from previous week)
– Cumulative cases per 100k: 27,225 (2,750 total cases)
— 11.0% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 535 (54 total deaths)
— 29.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 55.6% (5,621 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#21. St. Clair County, AL

– New cases per 100k in the past week: 353 (316 new cases, +12% change from previous week)
– Cumulative cases per 100k: 32,719 (29,287 total cases)
— 6.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 478 (428 total deaths)
— 16.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 39.9% (35,736 fully vaccinated)

Tracy Burroughs Brown // Shutterstock

#20. Tuscaloosa County, AL

– New cases per 100k in the past week: 361 (755 new cases, +19% change from previous week)
– Cumulative cases per 100k: 30,849 (64,584 total cases)
— 0.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 385 (807 total deaths)
— 6.6% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.6% (93,373 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#19. Hale County, AL

– New cases per 100k in the past week: 362 (53 new cases, +66% change from previous week)
– Cumulative cases per 100k: 36,421 (5,336 total cases)
— 19.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 744 (109 total deaths)
— 80.6% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 62.3% (9,125 fully vaccinated)

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#18. Marshall County, AL

– New cases per 100k in the past week: 371 (359 new cases, -27% change from previous week)
– Cumulative cases per 100k: 31,445 (30,431 total cases)
— 2.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 412 (399 total deaths)
— 0.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 46.6% (45,138 fully vaccinated)

Myself – Nathon Morris // Wikimedia Commons

#17. Lamar County, AL

– New cases per 100k in the past week: 391 (54 new cases, +12% change from previous week)
– Cumulative cases per 100k: 31,170 (4,303 total cases)
— 1.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 493 (68 total deaths)
— 19.7% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.9% (6,192 fully vaccinated)

Dailynetworks // Wikimedia Commons

#16. Colbert County, AL

– New cases per 100k in the past week: 393 (217 new cases, -23% change from previous week)
– Cumulative cases per 100k: 34,670 (19,152 total cases)
— 13.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 482 (266 total deaths)
— 17.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.8% (26,955 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#15. Butler County, AL

– New cases per 100k in the past week: 396 (77 new cases, +7% change from previous week)
– Cumulative cases per 100k: 30,440 (5,920 total cases)
— 0.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 663 (129 total deaths)
— 60.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 40.3% (7,830 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#14. Limestone County, AL

– New cases per 100k in the past week: 397 (393 new cases, -1% change from previous week)
– Cumulative cases per 100k: 29,312 (28,994 total cases)
— 4.2% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 305 (302 total deaths)
— 26.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 39.6% (39,165 fully vaccinated)

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#13. Perry County, AL

– New cases per 100k in the past week: 415 (37 new cases, +19% change from previous week)
– Cumulative cases per 100k: 27,278 (2,434 total cases)
— 10.9% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 527 (47 total deaths)
— 27.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 49.6% (4,425 fully vaccinated)

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#12. Winston County, AL

– New cases per 100k in the past week: 432 (102 new cases, +40% change from previous week)
– Cumulative cases per 100k: 35,930 (8,490 total cases)
— 17.4% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 567 (134 total deaths)
— 37.6% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 22.3% (5,274 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#11. Barbour County, AL

– New cases per 100k in the past week: 433 (107 new cases, +10% change from previous week)
– Cumulative cases per 100k: 27,372 (6,757 total cases)
— 10.6% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 409 (101 total deaths)
— 0.7% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 46.7% (11,522 fully vaccinated)

Mccallk69 // Shutterstock

#10. Macon County, AL

– New cases per 100k in the past week: 459 (83 new cases, +46% change from previous week)
– Cumulative cases per 100k: 25,969 (4,692 total cases)
— 15.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 487 (88 total deaths)
— 18.2% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 49.3% (8,900 fully vaccinated)

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#9. Bibb County, AL

– New cases per 100k in the past week: 460 (103 new cases, -18% change from previous week)
– Cumulative cases per 100k: 33,018 (7,394 total cases)
— 7.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 469 (105 total deaths)
— 13.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 35.8% (8,011 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#8. Cullman County, AL

– New cases per 100k in the past week: 473 (396 new cases, +20% change from previous week)
– Cumulative cases per 100k: 33,892 (28,391 total cases)
— 10.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 449 (376 total deaths)
— 9.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 38.7% (32,454 fully vaccinated)

MPearsallArt // Wikimedia Commons

#7. Morgan County, AL

– New cases per 100k in the past week: 473 (566 new cases, -6% change from previous week)
– Cumulative cases per 100k: 35,107 (42,016 total cases)
— 14.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 440 (526 total deaths)
— 6.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.4% (53,101 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#6. Tallapoosa County, AL

– New cases per 100k in the past week: 476 (192 new cases, +26% change from previous week)
– Cumulative cases per 100k: 32,851 (13,261 total cases)
— 7.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 609 (246 total deaths)
— 47.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 39.2% (15,826 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#5. Talladega County, AL

– New cases per 100k in the past week: 514 (411 new cases, -31% change from previous week)
– Cumulative cases per 100k: 32,558 (26,039 total cases)
— 6.4% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 478 (382 total deaths)
— 16.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 37.3% (29,801 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#4. Coosa County, AL

– New cases per 100k in the past week: 525 (56 new cases, +17% change from previous week)
– Cumulative cases per 100k: 32,224 (3,436 total cases)
— 5.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 563 (60 total deaths)
— 36.7% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 41.4% (4,419 fully vaccinated)

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#3. Walker County, AL

– New cases per 100k in the past week: 531 (337 new cases, +10% change from previous week)
– Cumulative cases per 100k: 34,293 (21,783 total cases)
— 12.1% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 718 (456 total deaths)
— 74.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.2% (30,638 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#2. Cleburne County, AL

– New cases per 100k in the past week: 617 (92 new cases, +557% change from previous week)
– Cumulative cases per 100k: 26,177 (3,903 total cases)
— 14.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 469 (70 total deaths)
— 13.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 29.3% (4,369 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#1. Franklin County, AL

– New cases per 100k in the past week: 762 (239 new cases, +88% change from previous week)
– Cumulative cases per 100k: 34,969 (10,967 total cases)
— 14.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 446 (140 total deaths)
— 8.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.6% (13,997 fully vaccinated)