Rudi Weikard // Wikimedia Commons

Counties with highest COVID-19 infection rates in Alabama

The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.

Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely.

The United States as of Nov. 16 reached over 1 million COVID-19-related deaths and 98.1 million COVID-19 cases, according to Johns Hopkins University. Currently, 68.6% of the population is fully vaccinated, and 10.1% of vaccinated people have received the most recently available bivalent booster doses.

Stacker compiled a list of the counties with highest COVID-19 infection rates in Alabama using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to Nov. 10, 2022. Cumulative cases per 100,000 served as a tiebreaker.

Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.

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#50. Wilcox County, AL

– New cases per 100k in the past week: 67 (7 new cases, +250% change from previous week)
– Cumulative cases per 100k: 33,327 (3,457 total cases)
— 6.1% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 463 (48 total deaths)
— 10.2% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 54.9% (5,696 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#49. Hale County, AL

– New cases per 100k in the past week: 68 (10 new cases, +67% change from previous week)
– Cumulative cases per 100k: 36,899 (5,406 total cases)
— 17.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 744 (109 total deaths)
— 77.1% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 62.7% (9,189 fully vaccinated)

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#48. Lawrence County, AL

– New cases per 100k in the past week: 70 (23 new cases, -21% change from previous week)
– Cumulative cases per 100k: 27,235 (8,967 total cases)
— 13.3% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 528 (174 total deaths)
— 25.7% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.0% (15,800 fully vaccinated)

Library of Congress

#47. Lee County, AL

– New cases per 100k in the past week: 72 (119 new cases, +102% change from previous week)
– Cumulative cases per 100k: 27,027 (44,471 total cases)
— 14.0% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 218 (359 total deaths)
— 48.1% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 41.7% (68,640 fully vaccinated)

Carol M. Highsmith/Library of Congress // Wikimedia Commons

#46. Houston County, AL

– New cases per 100k in the past week: 73 (77 new cases, +51% change from previous week)
– Cumulative cases per 100k: 28,867 (30,565 total cases)
— 8.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 497 (526 total deaths)
— 18.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.4% (46,996 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#45. Monroe County, AL

– New cases per 100k in the past week: 77 (16 new cases, +433% change from previous week)
– Cumulative cases per 100k: 29,947 (6,209 total cases)
— 4.7% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 410 (85 total deaths)
— 2.4% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.5% (9,223 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#44. Barbour County, AL

– New cases per 100k in the past week: 81 (20 new cases, +400% change from previous week)
– Cumulative cases per 100k: 28,154 (6,950 total cases)
— 10.4% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 417 (103 total deaths)
— 0.7% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.0% (11,598 fully vaccinated)

Wmr36104 // Wikimedia Commons

#43. Geneva County, AL

– New cases per 100k in the past week: 84 (22 new cases, +16% change from previous week)
– Cumulative cases per 100k: 28,594 (7,512 total cases)
— 9.0% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 651 (171 total deaths)
— 55.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 41.1% (10,803 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#42. Covington County, AL

– New cases per 100k in the past week: 84 (31 new cases, -28% change from previous week)
– Cumulative cases per 100k: 29,801 (11,041 total cases)
— 5.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 686 (254 total deaths)
— 63.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 38.8% (14,393 fully vaccinated)

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#41. Walker County, AL

– New cases per 100k in the past week: 91 (58 new cases, +61% change from previous week)
– Cumulative cases per 100k: 35,439 (22,511 total cases)
— 12.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 746 (474 total deaths)
— 77.6% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.4% (30,766 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#40. Franklin County, AL

– New cases per 100k in the past week: 92 (29 new cases, -19% change from previous week)
– Cumulative cases per 100k: 36,331 (11,394 total cases)
— 15.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 472 (148 total deaths)
— 12.4% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.9% (14,066 fully vaccinated)

Calvin Beale // Wikimedia Commons

#39. Coffee County, AL

– New cases per 100k in the past week: 94 (49 new cases, +58% change from previous week)
– Cumulative cases per 100k: 30,839 (16,142 total cases)
— 1.8% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 464 (243 total deaths)
— 10.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.4% (25,338 fully vaccinated)

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#38. Pickens County, AL

– New cases per 100k in the past week: 95 (19 new cases, +27% change from previous week)
– Cumulative cases per 100k: 30,316 (6,042 total cases)
— 3.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 562 (112 total deaths)
— 33.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 51.6% (10,279 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#37. Tallapoosa County, AL

– New cases per 100k in the past week: 97 (39 new cases, +117% change from previous week)
– Cumulative cases per 100k: 33,869 (13,672 total cases)
— 7.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 617 (249 total deaths)
— 46.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 39.4% (15,901 fully vaccinated)

Michael Rivera // Wikimedia Commons

#36. Dale County, AL

– New cases per 100k in the past week: 98 (48 new cases, +60% change from previous week)
– Cumulative cases per 100k: 31,652 (15,564 total cases)
— 0.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 496 (244 total deaths)
— 18.1% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 49.1% (24,149 fully vaccinated)

Tracy Burroughs Brown // Shutterstock

#35. Tuscaloosa County, AL

– New cases per 100k in the past week: 101 (212 new cases, +98% change from previous week)
– Cumulative cases per 100k: 31,737 (66,444 total cases)
— 1.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 397 (831 total deaths)
— 5.5% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.0% (94,293 fully vaccinated)

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#34. DeKalb County, AL

– New cases per 100k in the past week: 103 (74 new cases, -1% change from previous week)
– Cumulative cases per 100k: 29,971 (21,433 total cases)
— 4.6% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 480 (343 total deaths)
— 14.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 34.9% (24,927 fully vaccinated)

Altairisfar // Wikimedia Commons

#33. Lowndes County, AL

– New cases per 100k in the past week: 103 (10 new cases, 0% change from previous week)
– Cumulative cases per 100k: 31,740 (3,087 total cases)
— 1.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 823 (80 total deaths)
— 96.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 53.1% (5,167 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#32. Coosa County, AL

– New cases per 100k in the past week: 103 (11 new cases, +57% change from previous week)
– Cumulative cases per 100k: 33,096 (3,529 total cases)
— 5.4% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 581 (62 total deaths)
— 38.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 41.7% (4,446 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#31. Cullman County, AL

– New cases per 100k in the past week: 103 (86 new cases, +51% change from previous week)
– Cumulative cases per 100k: 35,419 (29,670 total cases)
— 12.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 458 (384 total deaths)
— 9.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 39.0% (32,682 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#30. Autauga County, AL

– New cases per 100k in the past week: 107 (60 new cases, +94% change from previous week)
– Cumulative cases per 100k: 33,240 (18,571 total cases)
— 5.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 410 (229 total deaths)
— 2.4% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.6% (25,452 fully vaccinated)

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#29. Baldwin County, AL

– New cases per 100k in the past week: 108 (240 new cases, +208% change from previous week)
– Cumulative cases per 100k: 29,661 (66,213 total cases)
— 5.6% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 321 (716 total deaths)
— 23.6% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 52.8% (117,771 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#28. Blount County, AL

– New cases per 100k in the past week: 114 (66 new cases, +94% change from previous week)
– Cumulative cases per 100k: 30,066 (17,386 total cases)
— 4.3% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 446 (258 total deaths)
— 6.2% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 32.7% (18,889 fully vaccinated)

Springfieldohio // Wikimedia Commons

#27. Jackson County, AL

– New cases per 100k in the past week: 114 (59 new cases, +181% change from previous week)
– Cumulative cases per 100k: 33,256 (17,169 total cases)
— 5.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 486 (251 total deaths)
— 15.7% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 50.8% (26,201 fully vaccinated)

Chris Pruitt // wikicommons

#26. Montgomery County, AL

– New cases per 100k in the past week: 115 (261 new cases, +137% change from previous week)
– Cumulative cases per 100k: 29,800 (67,493 total cases)
— 5.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 442 (1,000 total deaths)
— 5.2% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 54.3% (122,921 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#25. Chambers County, AL

– New cases per 100k in the past week: 117 (39 new cases, +77% change from previous week)
– Cumulative cases per 100k: 30,306 (10,078 total cases)
— 3.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 508 (169 total deaths)
— 21.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 32.9% (10,943 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#24. Elmore County, AL

– New cases per 100k in the past week: 118 (96 new cases, +134% change from previous week)
– Cumulative cases per 100k: 34,414 (27,947 total cases)
— 9.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 441 (358 total deaths)
— 5.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.9% (38,884 fully vaccinated)

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#23. Marshall County, AL

– New cases per 100k in the past week: 121 (117 new cases, +166% change from previous week)
– Cumulative cases per 100k: 32,240 (31,200 total cases)
— 2.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 419 (405 total deaths)
— 0.2% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.0% (45,498 fully vaccinated)

Prestinian // Wikimedia Commons

#22. Etowah County, AL

– New cases per 100k in the past week: 127 (130 new cases, +40% change from previous week)
– Cumulative cases per 100k: 31,896 (32,619 total cases)
— 1.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 669 (684 total deaths)
— 59.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 42.1% (43,100 fully vaccinated)

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#21. Bibb County, AL

– New cases per 100k in the past week: 129 (29 new cases, +93% change from previous week)
– Cumulative cases per 100k: 33,956 (7,604 total cases)
— 8.1% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 482 (108 total deaths)
— 14.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 36.1% (8,080 fully vaccinated)

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#20. Fayette County, AL

– New cases per 100k in the past week: 129 (21 new cases, +31% change from previous week)
– Cumulative cases per 100k: 34,474 (5,620 total cases)
— 9.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 601 (98 total deaths)
— 43.1% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 36.0% (5,864 fully vaccinated)

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#19. Pike County, AL

– New cases per 100k in the past week: 133 (44 new cases, +300% change from previous week)
– Cumulative cases per 100k: 26,590 (8,805 total cases)
— 15.4% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 423 (140 total deaths)
— 0.7% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 43.4% (14,358 fully vaccinated)

M Floyd // Flickr

#18. Jefferson County, AL

– New cases per 100k in the past week: 142 (934 new cases, +104% change from previous week)
– Cumulative cases per 100k: 33,662 (221,687 total cases)
— 7.2% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 377 (2,480 total deaths)
— 10.2% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 60.6% (398,959 fully vaccinated)

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#17. Colbert County, AL

– New cases per 100k in the past week: 147 (81 new cases, +56% change from previous week)
– Cumulative cases per 100k: 35,725 (19,735 total cases)
— 13.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 491 (271 total deaths)
— 16.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 49.1% (27,102 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#16. Shelby County, AL

– New cases per 100k in the past week: 148 (322 new cases, +139% change from previous week)
– Cumulative cases per 100k: 33,256 (72,400 total cases)
— 5.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 217 (473 total deaths)
— 48.3% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 37.4% (81,443 fully vaccinated)

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#15. Winston County, AL

– New cases per 100k in the past week: 148 (35 new cases, +67% change from previous week)
– Cumulative cases per 100k: 37,560 (8,875 total cases)
— 19.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 584 (138 total deaths)
— 39.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 22.4% (5,304 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#14. Calhoun County, AL

– New cases per 100k in the past week: 151 (171 new cases, +151% change from previous week)
– Cumulative cases per 100k: 34,079 (38,716 total cases)
— 8.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 582 (661 total deaths)
— 38.6% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.5% (55,076 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#13. Cherokee County, AL

– New cases per 100k in the past week: 153 (40 new cases, +90% change from previous week)
– Cumulative cases per 100k: 23,286 (6,100 total cases)
— 25.9% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 332 (87 total deaths)
— 21.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 31.8% (8,339 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#12. Marion County, AL

– New cases per 100k in the past week: 155 (46 new cases, +156% change from previous week)
– Cumulative cases per 100k: 31,947 (9,491 total cases)
— 1.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 525 (156 total deaths)
— 25.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 37.2% (11,037 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#11. Limestone County, AL

– New cases per 100k in the past week: 159 (157 new cases, +128% change from previous week)
– Cumulative cases per 100k: 30,419 (30,089 total cases)
— 3.2% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 311 (308 total deaths)
— 26.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 40.0% (39,534 fully vaccinated)

MPearsallArt // Wikimedia Commons

#10. Morgan County, AL

– New cases per 100k in the past week: 160 (192 new cases, +64% change from previous week)
– Cumulative cases per 100k: 36,428 (43,597 total cases)
— 16.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 450 (538 total deaths)
— 7.1% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.7% (53,446 fully vaccinated)

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#9. Madison County, AL

– New cases per 100k in the past week: 178 (664 new cases, +129% change from previous week)
– Cumulative cases per 100k: 29,198 (108,883 total cases)
— 7.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 277 (1,033 total deaths)
— 34.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 64.6% (240,786 fully vaccinated)

Wayne James // Shutterstock

#8. Lauderdale County, AL

– New cases per 100k in the past week: 183 (170 new cases, +102% change from previous week)
– Cumulative cases per 100k: 30,862 (28,618 total cases)
— 1.8% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 443 (411 total deaths)
— 5.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.0% (44,501 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#7. Talladega County, AL

– New cases per 100k in the past week: 184 (147 new cases, +568% change from previous week)
– Cumulative cases per 100k: 33,689 (26,944 total cases)
— 7.2% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 488 (390 total deaths)
— 16.2% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 37.6% (30,034 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#6. Randolph County, AL

– New cases per 100k in the past week: 238 (54 new cases, -17% change from previous week)
– Cumulative cases per 100k: 26,609 (6,046 total cases)
— 15.3% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 339 (77 total deaths)
— 19.3% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 33.9% (7,703 fully vaccinated)

Myself – Nathon Morris // Wikimedia Commons

#5. Lamar County, AL

– New cases per 100k in the past week: 246 (34 new cases, +55% change from previous week)
– Cumulative cases per 100k: 32,532 (4,491 total cases)
— 3.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 500 (69 total deaths)
— 19.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.1% (6,231 fully vaccinated)

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#4. Bullock County, AL

– New cases per 100k in the past week: 267 (27 new cases, +2,600% change from previous week)
– Cumulative cases per 100k: 28,166 (2,845 total cases)
— 10.3% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 535 (54 total deaths)
— 27.4% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 56.3% (5,684 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#3. Cleburne County, AL

– New cases per 100k in the past week: 268 (40 new cases, +122% change from previous week)
– Cumulative cases per 100k: 28,008 (4,176 total cases)
— 10.8% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 476 (71 total deaths)
— 13.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 29.4% (4,387 fully vaccinated)

JNix // Shutterstock

#2. Clay County, AL

– New cases per 100k in the past week: 340 (45 new cases, +137% change from previous week)
– Cumulative cases per 100k: 36,456 (4,825 total cases)
— 16.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 680 (90 total deaths)
— 61.9% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 43.2% (5,720 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#1. St. Clair County, AL

– New cases per 100k in the past week: 347 (311 new cases, +364% change from previous week)
– Cumulative cases per 100k: 34,217 (30,628 total cases)
— 8.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 485 (434 total deaths)
— 15.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 40.2% (35,965 fully vaccinated)